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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NKX3-1
All Species:
14.55
Human Site:
Y217
Identified Species:
26.67
UniProt:
Q99801
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q99801
NP_006158.2
234
26350
Y217
L
V
S
V
Y
N
S
Y
P
Y
Y
P
Y
L
Y
Chimpanzee
Pan troglodytes
XP_001159503
229
26021
Y212
L
V
S
V
Y
N
S
Y
P
Y
Y
P
Y
L
Y
Rhesus Macaque
Macaca mulatta
XP_001106332
232
26111
Y215
L
V
S
L
Y
N
N
Y
P
Y
Y
P
Y
L
Y
Dog
Lupus familis
XP_543240
206
23431
P190
I
S
M
H
N
S
Y
P
Y
Y
P
Y
L
Y
C
Cat
Felis silvestris
Mouse
Mus musculus
P97436
237
26806
T218
T
S
L
V
S
V
Y
T
S
Y
P
Y
Y
P
Y
Rat
Rattus norvegicus
P23441
372
38536
Q254
Q
Q
Q
Q
A
Q
Q
Q
S
P
R
R
V
A
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507333
521
57733
Y504
L
I
S
M
Y
N
S
Y
P
Y
Y
P
Y
F
Y
Chicken
Gallus gallus
Q90788
294
33054
P212
P
C
L
G
E
S
S
P
Y
S
S
P
Y
N
V
Frog
Xenopus laevis
Q9W7E8
213
24704
Q197
L
S
F
Y
Q
N
Y
Q
R
Y
P
Y
L
Y
Y
Zebra Danio
Brachydanio rerio
Q90481
269
30288
Q218
P
C
H
T
L
K
A
Q
D
L
A
A
T
F
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P22809
382
41975
A268
T
T
Y
A
H
M
A
A
P
G
A
G
H
G
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q9NLC2
299
33058
D243
K
Y
S
I
E
M
D
D
K
D
D
E
E
E
E
Sea Urchin
Strong. purpuratus
Q26656
405
44721
Q346
V
H
V
H
A
Y
A
Q
R
M
V
R
V
P
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
93.1
91.4
58.9
N.A.
66.2
22.5
N.A.
33.7
28.2
44.4
23.7
N.A.
23.8
N.A.
25.4
25.4
Protein Similarity:
100
94
93.5
67.5
N.A.
73.4
33.5
N.A.
37.6
39.7
58.9
36.4
N.A.
37.4
N.A.
36.7
36.5
P-Site Identity:
100
100
86.6
6.6
N.A.
26.6
0
N.A.
80
20
26.6
0
N.A.
6.6
N.A.
6.6
0
P-Site Similarity:
100
100
100
20
N.A.
26.6
0
N.A.
93.3
26.6
26.6
6.6
N.A.
26.6
N.A.
13.3
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
8
16
0
24
8
0
0
16
8
0
8
0
% A
% Cys:
0
16
0
0
0
0
0
0
0
0
0
0
0
0
8
% C
% Asp:
0
0
0
0
0
0
8
8
8
8
8
0
0
0
0
% D
% Glu:
0
0
0
0
16
0
0
0
0
0
0
8
8
8
8
% E
% Phe:
0
0
8
0
0
0
0
0
0
0
0
0
0
16
0
% F
% Gly:
0
0
0
8
0
0
0
0
0
8
0
8
0
8
0
% G
% His:
0
8
8
16
8
0
0
0
0
0
0
0
8
0
0
% H
% Ile:
8
8
0
8
0
0
0
0
0
0
0
0
0
0
8
% I
% Lys:
8
0
0
0
0
8
0
0
8
0
0
0
0
0
0
% K
% Leu:
39
0
16
8
8
0
0
0
0
8
0
0
16
24
8
% L
% Met:
0
0
8
8
0
16
0
0
0
8
0
0
0
0
0
% M
% Asn:
0
0
0
0
8
39
8
0
0
0
0
0
0
8
0
% N
% Pro:
16
0
0
0
0
0
0
16
39
8
24
39
0
16
0
% P
% Gln:
8
8
8
8
8
8
8
31
0
0
0
0
0
0
8
% Q
% Arg:
0
0
0
0
0
0
0
0
16
0
8
16
0
0
0
% R
% Ser:
0
24
39
0
8
16
31
0
16
8
8
0
0
0
0
% S
% Thr:
16
8
0
8
0
0
0
8
0
0
0
0
8
0
0
% T
% Val:
8
24
8
24
0
8
0
0
0
0
8
0
16
0
16
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
8
8
8
31
8
24
31
16
54
31
24
47
16
47
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _